Lauren and Katie, college frenemies with a mutual good friend, move in together at age 28 in order to afford an amazing Gramercy Park apartment. The unlikely pair start a phone sex line and become best friends while learning about this hilarious world of vibrators, fake orgasms and nighttime callers. When the hot line is hung up and reality comes calling, the most meaningful relationship of their lives is put to the test.

In a working class neighborhood in Los Angeles, a world weary Henry Poole buys a house, caring little about its lack of amenities. He drinks and eats pizza. Recent stucco work has left a brown stain in a patio wall, and, to Henry's irritation, Esperanza, a neighbor, is certain she can see the face of Jesus in the stain. She brings her priest, then others. Meanwhile, Henry hears his conversations replayed over the fence in another neighbor's yard: it's Millie, about 7, mute, clutching a tape recorder. He tells Millie's mom why he's sad and angry. The face on the wall seems to shed a tear of blood. Is Henry beyond feeling any emotion?